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My interest has been piqued. Tell me how do you wish to do this? One by one with the crew trying to come to terms with the strange goings on? Make all of Planet Express Fry's harem/other at once? tranform them all retroactively and go on sexy adventures from there? Or make it retroactive and show the new Futurama starting from when Fry woke from Cryo?
So ideas that I had were for during "Bend-Her" for Bender to have remained a Fembot for too long and is unable to change back after the whole faked death/interrupted funeral. The Prof then constructs synthetic skins (like with Robot Leela and Fry) that makes her look like a sexy latina (so as to avoid people recognizing Calculon's dead lover).
Zoidberg being born female and a sexy nurse, during the mating season on her planet she turned down every would be mate to bed Fry instead. Unable to impregnate her, she survives the encounter.
Meant interrupted wedding.